LRIDE (LEVOSULPRIDE INJECTION & TABLETS)

DESCRIPTION

Levosulpiride is a substituted benzamide antipsychotic, reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent. Levosulpiride is also claimed to have mood elevating properties. Levosulpiride is used in the treatment of psychoses, particularly negative symptoms of schizophrenia.

DOSAGE

Gastro-oesophageal reflux disease, Irritable bowel syndrome, Dyspepsia

Adult: 25 mg tid. Elderly: Dose reductions may be necessary.

CLINICAL PHARMACOLOGY

INDICATIONS

Psychoses, Schizophrenia, Anxiety Disorders, Dysthymia, Vertigo, Dyspepsia, Irritable Bowel Syndrome and Premature Ejaculation.

CONTRA INDICATIONS

Phaeochromocytoma, epilepsy, manic states, hyperprolactinaemia, mammary dysplasia, malignant mastopathies, cardiac impairment. GI bleeding, mechanical obstruction or perforation.

SIDE EFFECTS

Side effects include amenorrhoea, gynaecomastia, galactorrhoea, changes in libido, and neuroleptic malignant syndrome. It also effects GI motility may be antagonized by anticholinergic agents, narcotics and analgesics.

DRUG INTERACTIONS

AVAILABILITY

LRIDE  is available in strips  of  ten  capsules containing LEVOSULPRIDE INJECTION & TABLETS.